Abstract:
Osteoarthritis (OA) is a progressive and degenerative joint condition affecting 30.8 million Americans and is estimated to affect 130 million people across the world by 2050. It is currently the 5th leading cause of disability worldwide; with earning losses greater than $80 billion per year (Maiese, 2016). Knee osteoarthritis (KOA) accounts for more than 80% of the condition’s total burden (Wallace et al., 2017). In addition to impacting quality of life, knee osteoarthritis is a major economic burden.
